Heart to Heart Foundation was founded in 1983 with a mission to support healthcare and medical research. In earlier years, the founders sponsored cardiology research at Georgetown University and also sponsored home healthcare. 

Today, Heart to Heart Foundation supports activities in integrative health, environmental health, and disaster recovery; including collaborative partnerships in community health and wellness, education and awareness, community outreach, coalition development, and interdisciplinary intervention (501c3, est. 1983).

Many activities are in collaboration with George Mason University's Center for Resilient, Adaptable, and Safe Communities (C-RASC) and STAR-TIDES. 

Heart to Heart Foundation supports multiple initiatives including: 

• Children of Heroes Fund: Advocates for youth who have lost a parent around their public service to our country as a first responder, member of the military, or similar service in public safety and national security; and violence prevention especially in K-12 and collegiate environments. Children of Heroes Fund is a 501c3 charity.
• Appalachia Recovery Coalition: Environmental health related disaster recovery and resilience development in the Appalachian region
• Farmers Across America: Supporting family owned farms and farmers markets in local community partnerships and grants 
• Central America: Hospital and medical development internationally, including integrative health collaborative and practitioner network development 

Heart to Heart Foundation is a nonprofit 501c3 organization. Contributions are tax deductible.